Time intertwines with each other, each era is connected to each other, and there are women who are deeply attracted to angels and whose appearance does not change with time. The big tree that governs the world appears only in front of these women, and it keeps releasing its spores. In this endless time, they survive between madness, happiness and curiosity. Faced with a series of out-of-the-ordinary events, Rin, who runs the Shinjuku office, and her assistant Mimi rebelled. The killer Lola, who was instructed by someone to stubbornly target Rin's life, the mysterious figure Eibers, who looks like a teenager but actually has an abnormal aesthetic consciousness and is of unknown age, and Sayero, a sadistic scientist and director of the Sayama Research Institute of Aoyama Pharmaceutical, and other characters, have appeared in front of Rin one after another.