Suffering from cancer, "Jigsaw" John Kramer (Tobin Bell) is dying. However, the "Jigsaw Murders" he created did not stop there, but became more and more serious. Police officer Mark Hoffman (Costas Mandylor) once used the name of "Jigsaw" to avenge the murderer who killed his family, but he soon became John's prey. After twists and turns, Hoffman became the successor of the "Jigsaw Murders", but John's original intention of warning the world and saving people was completely abandoned, replaced by endless bloody killings. A five-person escape game with no chance of winning was hosted by Hoffman. On the other hand, Hoffman tried every means to conceal his identity, but police officer Pete Stram (Scott Patterson) began to doubt him. Stram tried every means to find evidence, but he never thought that he had walked into the cruel maze set by Hoffman...