The war between werewolves and vampires continues. While Michael (Scott Speedman) and Selene (Kate Beckinsale) are still trying to stop the war with their weak abilities, the conspirators' masterpiece is born again - a race with super powers that is a fusion of werewolves and vampires - the "blood race". Max (Tony Curran) is the second generation of this race. He killed his father, seized the key and Selene's memory, and rescued the twin brothers who were imprisoned for a thousand years, one was a werewolf and the other was a vampire, in an attempt to unify the three major races of werewolves, vampires and humans. For love, the lovers Michael and Selene must thwart Max's conspiracy and defeat the twin brothers who have been imprisoned for a thousand years...