Jigsaw (Tobin Bell) and his new apprentice Amanda disappeared, and the police searched everywhere, and the whole city was covered with dark clouds. One night, female doctor Lane Darren (Bahar Soomekh), who had just finished her night shift, was kidnapped. When she woke up, Lane was terrified and found herself tied up in an abandoned empty house with another unlucky victim Jeff (Angus Macfadyen). At this time, Jigsaw was bedridden and dying. Lane was told that unless she could save the life of this madman before the death game was completed, she and Jeff would definitely die! In order to survive, Lane, who was highly nervous and tormented, tried her best to let Jigsaw keep his last breath. However, she could never have imagined that the killer secretly had a more terrible killing plan-that would be the notorious Jigsaw's painstaking pre-death brilliance! The final ultimate death game is about to begin...