The story takes place in a small town in the western United States in the 17th century, where the mute girl Lizzie (Dakota Fanning) and her husband Eli (William Houston) live there with their children. Although the days are poor and Lizzie is born with disabilities, both are satisfied with the current stable life. One day, a priest (Guy Pearce) came to the town. When she saw the priest for the first time, Lizzie knew that her happy life would be gone forever. What kind of festival did the priest and Lizzie have that he would persecute her and her family so ruthlessly? Lizzie is a midwife. During an operation, the pregnant woman was in danger of life. When only one of the mother and the child could be saved, Lizzie chose to protect her mother. However, this choice also pushed her into an abyss of eternal damnation.