Pedraza is a remote town in Spain that is plagued by inexplicable demonic events, leaving most of its inhabitants losing their minds and locked up in mental hospitals. Elena (Megan Montaner) lies in a coma in a Madrid hospital bed, while Paco (Miguel Ángel Silvestre), who is broken by remorse, tries to care for her. As the terror intensifies, the protagonists must face a mysterious new enemy (Paul Giamatti) - a man so twisted that even demons fear him.