The story tells about Abby Arcane, a doctor from the Centers for Disease Control, who went to a swamp in her hometown to investigate a deadly infectious virus, only to discover something mysterious and terrifying in the swamp... Arcane is a smart, caring woman. Her encounter with scientist Alec Holland allowed her to learn about a new world full of terror and supernatural power, as well as the powerful and terrifying creature "Swamp Monster". Holland's research on the swamp allowed him to discover some secrets, which led to the dark power, and he became the powerful hero Swamp Monster. The monster is doing his best to maintain the remaining humanity, and he must adapt to his new identity as soon as possible to protect the town and the natural world outside.