The troublemaker Fan Xiaoxian (played by Zhang Liang) and the righteous girl Li Xin (played by Zhang Yuqi) have been incompatible since childhood. After a dispute, Fan Xiaoxian cursed Li Xin that she would never get married. After growing up, although Fan Xiaoxian had a successful career, he encountered a double crisis of marriage and health. Li Xin also remained single and became a leftover woman as he "cursed"... A pair of enemies who could break out at any time and constantly argue, with their own ulterior motives, squeezed into the same car and drove on the beautiful highway of America...