16 years ago, Sagittarius Gold Saint Aiolos escaped from the Sanctuary with the real goddess Athena in his arms. On the way, he was blocked by Gemini Saka and Capricorn Shura and was seriously injured. Under the trend of fate, Aiolos, who was on the verge of death, entrusted the goddess to the president of the Japanese Kido Group, Kido Mitsumasa (voiced by Osugi Ren), who happened to come to the Himalayas for an adventure. Knowing the cause and effect, Mitsumasa brought the goddess back to Japan, named her Saori, and raised her as his granddaughter. Accepting the call of fate and the goddess, after hard training, Seiya (voiced by Kaito Ishikawa), Shiryu (voiced by Kenji Akabane), Hyoga (voiced by Kensho Ono), Shun (voiced by Nobuhiko Okamoto) and other teenagers returned to Japan one after another. Now they have grown into Saints who can stand on their own. At the same time, assassins ordered by the Pope came to Japan from the Sanctuary one after another, and a battle between good and evil that was enough to be recorded in the annals of history began...