Wu Yingxiong (played by Mark Chao), a police officer suspected of "violent tendencies", staged a life-and-death car chase drama for the first time he handled a case, crashing several streets. He was ordered to stop handling the case, but he was still tracking a bizarre case. At the other end of Harbour City, Xu Dafu (played by Huang Bo), a gangster office worker who claimed to be a "third-level cadre of the Tri-Union", embezzled gang black money to smuggle diamonds for a woman. During the transaction, he was suddenly shot by a mysterious team. Wu Yingxiong, who came to the scene in the chaos, thought it was just a black market transaction, but after catching Xu Dafu, a disaster began... Under the serial killings of a mysterious foreign killer (played by Angelababy) in the special police force, and the city-wide pursuit of helicopters, heavy machine guns and rockets, a policeman with an excessive sense of justice and a gangster with a sense of humor had to form an alternative "duo". In addition to escaping, they had to face a catastrophe, because the box containing diamonds was not that simple. In 36 hours, Harbour City will be destroyed, and the real enemy seems to always be one step faster than them...