Deep in the eerie and terrifying ghost forest, stands a majestic castle. The owner here is the famous vampire Dracula (voiced by Adam Sandler). Unlike the legend, Dracula is an extremely gentle and good father. He raised his beloved daughter Mavis (voiced by Selena Gomez) alone. In order to protect his daughter from being killed by humans, he specially built this castle called Screaming Hotel. Ordinary humans can never get close to it. Every year on Mavis' birthday, monsters such as Frankenstein, werewolves, mummies, and invisible men come from all over the world to celebrate the little girl's birthday. On Mavis' 118th birthday, she was eager to see the outside world. Dracula, who had been prepared, set up a scam, but accidentally introduced the human boy Jonathan (voiced by Andy Samberg) into the castle. Jonathan's arrival seems to bring a new breath to the monster world, and Count Dracula has to go to great lengths to hide the truth that he is a human...