Six friends: Cindy (Anna Faris), Bobby (Jon Abrahams), Buffo (Shannon Elizabeth), Greg (Lochlyn Munro), Ray (Shawn Wayans), and Brenda (Regina Hall) are now in deep trouble, being stalked by a serial killer. The incident originated from a car accident when they were driving home on Halloween night last year. In order to evade responsibility, they did not call the police but chose to flee the scene. Now, a serial killer who claims to know their affairs seems to have walked out of a horror movie and entered their lives. The six friends will have to find ways to escape from the clutches of the killer and those annoying reporters if they want to survive...