GiGi (Ginnifer Goodwin) is a girl who is full of fantasy about love, but she is frustrated in one date after another. Her besties Beth (Jennifer Aniston) and Janine (Jennifer Connelly) constantly encourage GiGi to cheer up in her relationship, but they each have regrets about love. Beth and Neil (Ben Affleck) have lived together for seven years, but they have never been able to wait for the wedding ring they have been waiting for. Janine's sensitivity has brought her marriage to Ben (Bradley Cooper) into a deadlock, and Ben's affair with singer Anna (Scarlett Johansson) has made their marriage even worse. Anna refuses the advances of her fan Conor (Kevin Connolly), while she passionately hopes that Ben will leave Janine, but can Ben really leave Janine and come to her side? On the other hand, Anna's friend Mary (Drew Barrymore) unexpectedly meets Conor face to face one morning. Several girls stumbled around in the city with their dreams of love, and at this time, GiGi, who had never met her true love, heard the words that broke the hearts of all women from the bar owner Alex (Justin Long): "He is just not that into you!"