A highly lethal and contagious virus spreads in the world. In order to escape, Danny (Lou Taylor Pucci), his brother Brian (Chris Pine), his girlfriend Bobby (Piper Perabo), and his friend Kate (Emily Wankep) drove through the deserts of the American Southwest at the fastest speed. They hope to find a relatively safe place, but after spending a whole few days, they realized that perhaps there is no place for them in this huge country. Not only is the raging of the virus oppressing everyone's nerves, they are also constantly forced to face the pressure created by moral and ethical decisions and challenges-all of which are difficult and human choices that they could not imagine before. Soon, they discovered that the biggest enemy in front of them was not the deadly bacteria or viruses that constantly attack and defeat mankind, but the darkness and evil hidden deep in their hearts...