On the night of July 27, 1976, a strong earthquake of magnitude 7.8 broke out in Tangshan, causing the collapse of houses and countless victims. Faced with the imminent collapse of the dangerous building, husband Fang Daqiang (played by Zhang Guoqiang) and wife Li Yuanni (played by Xu Fan) both went to rescue the trapped twins Fang Deng (played by Zhang Zifeng) and Fang Da (played by Zhang Jiajun). At the critical moment, Fang Daqiang stopped his wife and unfortunately died when he rushed in to rescue. After the earthquake, Li Yuanni found that her children were trapped at both ends of a cement slab. If they were to be rescued, one of them would have to be sacrificed. In a hurry, she made a difficult choice - to save her brother. This incident became an indelible pain in Fang Deng's heart. Later, she was adopted by the soldier Wang Deqing (played by Chen Daoming) and his wife. After the college entrance examination, Fang Deng (played by Zhang Jingchu) entered Hangzhou Medical College and developed feelings with his graduate student brother Yang Zhi (played by Lu Yi)... Fang Da was rescued but broke his arm, and Li Yuanni raised him with selfless maternal love. As an adult, Fang Da (played by Li Chen) went to Hangzhou to make a living, married his wife Xiao He (played by Wang Ziwen), and started a career. 32 years later, the fate of this family overlapped again because of the 5.12 Wenchuan earthquake...