The story takes place in the home of famous exorcists Ed and Lorraine Warren, a couple of demonology consultants. They perform exorcisms for people in need in various places. In order to prevent these evil spirits from harming the world again, they bring back the objects that are cursed, possessed by ghosts, or even used in cult rituals, and store them in the artifact room and the paranormal museum for preservation. They also invite priests to pray and purify them at fixed times. Annabelle, who is so evil that even Lorraine Warren doesn't want to face it directly, is one of the objects "collected" by the Warrens' Paranormal Museum. On an unclean night, the door to the Warrens' Paranormal Museum was opened, and a friend of the Warrens' daughter Judy entered the museum. Not knowing the seriousness of the situation, she inadvertently released Annabelle, leading all the released evil spirits in the museum. The awakened Annabelle and the evil spirits have a new target: the Warrens' daughter Judy and her good friend...