Agent Hannaway (Josh Holloway) was killed while on a mission, and the nuclear confidential documents were intercepted by the female killer Moran (Léa Seydoux). In order to retrieve the documents, Agent Bangui (Simon Pegg) and Agent Jane (Paula Patton) rescued Ethan Hunt (Tom Cruise) from a Russian prison. The ghost agreement mission they accepted was to steal the nuclear military codes from the Kremlin. However, when they approached the target, they found that the terrorist Hendrix (Michael Nyqvist) had taken the lead and snatched the nuclear military codes. In the explosion, Hunter was trapped in the hospital and was hunted by Russian agents. Fortunately, he was agile and escaped danger. However, Hunt's boss also died in the chaos, leaving only his assistant Brand (Jeremy Renner) and Hunt to survive. Together with Benji and Jane, the four men who were forced into a last-ditch struggle began a final fight. From Dubai to India, they went through life and death, and fought the terrorists' wits and courage.