Lin Xijia (played by Anthony Wong), a professor at the famous university's medical school, specializes in studying how humans can go without sleep for a long time. One day, his ex-girlfriend Qiu Mengxi (played by Wu Lixuan) suddenly appeared for help. It turned out that all her family members suffered from insomnia. When the disease reached the terminal stage, the patient would fall into an abnormal state and be extremely aggressive! In order to find out the truth, Lin Xijia started a series of horrific experiments: sneaking into the morgue to steal the patient's brain, and locking Qiu Mengxi in a secret room to study the relationship between sleep and brain protein... As the experiment went deeper, strange things kept happening to Qiu Mengxi; even Lin Xijia seemed to be infected, and began to have the desire to eat human flesh... It turned out that everything was related to an ethical tragedy 45 years ago between twin sisters Hou Wenyuan and Hou Wenzhen (played by Wai Shiya)!