Anne (Awkwafina), a smart girl obsessed with the famous quiz show Can't Stop Quiz, is now forced to reunite with her estranged sister Jenny (Sandra Oh), who is in a mess, because their mother owes gambling debts and they must team up to pay for it. So the sisters embark on a wild journey across America, desperate to win enough money to pay off the debt, and the only way to do that is to make our reluctant protagonist become a true Can't Stop Quiz champion.