After turning over a new leaf, Gru (voice of Steve Carell Steve Carell) has achieved impressive results as a spy, but because he failed to defeat the bad boy Balthazar Brad (voice of Trey Parker Trey Parker) was kicked out by the new director. At this moment, he received a letter from afar, and only then did he learn that he had a twin brother Drew (voice of Steve Carell Steve Carell). At Drew's kind invitation, Gru brought his wife Lucy Wilde (voice of Kristen Wiig Kristen Wiig) and Margo (voice of Miranda Cosgrove Miranda Cosgrove), Edith (voice of Dana Gaier Dana Gaier) and Agnes (voice of Elsie Fisher Elsie Fisher) to visit his biological father's place where he lives. Drew is innocent, but he wants to partner with his brother to become a badass duo. Although Gru has temporarily returned to the wild, his heart of justice has not been wiped out. Especially when Balthazar's evil plan involved three lovely children, he could no longer sit idly by...