At Kennedy International Airport under the cover of night, a flight from Berlin landed silently on the abandoned runway. The strange incident attracted the attention of various departments. Ephraim Goodwinzer (Corey Stoll), the chief medical officer of the New York region of the US Centers for Disease Control and Prevention, led his men into the cabin and found that more than 200 passengers had mysteriously died without any consciousness. Never seen parasites, the suddenly resurrected dead, the strangely disappeared giant coffin, and the official vague and obvious rhetoric all cast a strange and dangerous veil over this incident. The warning of the Jewish old man Abraham Setrakian (David Bradley) is still fresh in his ears, and the successive murders lead Iver to an unknown direction. Is it an alien invasion? Or is it the spread of a mysterious virus? Or is it the vampire in the ancient legend? The future is confusing...