Psychotherapist Ben (Dylan McDermott) was discovered by his wife Vivien (Connie Britton) for having an affair with a female student. After coordination, he decided to move to Los Angeles with his daughter Violet and her family to start a new life. But all kinds of strange people came one after another: the old and young maid Moira (Alexandra Breckenridge); the strange girl Adelaide who can predict the future; the mysterious man in a black tight rubber suit; the patient Tate (Evan Peters) with a head full of weird ideas, the uninvited neighbor Constance (Jessica Lange), and the chilling stalker Larry (Denis O'Hare). The monsters in the basement; the lingering ghosts; the secret experiments in the jars and cans, these bizarre events also seem to confirm that this house hides unspeakable mysteries...