Ren Xinzheng (Wu Gang), a professor at the University of Traditional Chinese Medicine, is committed to spreading Chinese medicine. He resigned and founded a Chinese medicine inheritance class, hoping to train successors who can truly pass on the way of Chinese medicine. The reckless Sun Tou Tou (Zhao Lusi) also unexpectedly joined the apprenticeship class. He is incompatible with Ren Xinzheng's son Ren Tianzhen (Luo Yizhou), and is incompatible with Yang Xiaohong (Zhang Meng), a lawyer who has changed his career, Peng Shiyan (Zhou Chengao), a pediatrician at a tertiary hospital, and Zhao Liquan (Zhu Junlin), who wants to become a famous doctor with the expectations of the whole village. This group of students who came with their own questions followed the teachers such as Ren Xinzheng and Song Linglan (Jiang Shan) who made great wishes, and moved forward in the direction of inheriting the orthodoxy in the midst of chaos, and learned to inherit the traditional Chinese medicine culture as a wave of the future.