This drama tells the story of Tang Jiayu, a female cardiac surgeon who has practiced medicine abroad for many years. She was invited by Vice President Liu Feng to return to China to serve as the director of the Heart Center of Beijing Anhe Jisheng Hospital. She first met the Director of the Medical Affairs Department, Ouyang Zhenyu, and then gradually became a close friend with the anesthesiologist Ye Yiming. At the same time, she led the five members of the critically ill team: Jiang Bailie, Long Xiangdong, Qin Dazhong, Zhou Da, and Liao Xiaobo to jointly treat 28 rare heart cases. In the continuous growth, she promoted the successful development of the domestic "all-magnetic levitation artificial heart", and finally rewrote the history of Chinese cardiac surgery, while achieving self-salvation and harvesting happiness.