After getting their super powers, many people with super powers still try to become ordinary people and live ordinary lives, but the mysterious organization HRG and the "brain eater" Saylor (Zachary Quinto) are unwilling to let them go. "Cheerleader" Claire (Hayden Panettiere) and her adoptive father Bennett (Jack Coleman) live in seclusion in California, but find that there are also HRG members hidden among their classmates; "Split Girl" Nikki (Ali Larter) is determined to lead a normal life with her son, but finds that she is being monitored; Pete (Milo Ventimiglia), who took the initiative to "nuclear explosion", has returned with a mysterious scar, as if he has become another person, and his entanglement with his brother Nathan (Adrian Pasdar) continues...