William Blake (Johnny Depp), an American young man from Cleveland, went to the West to make a living. He was going to a local factory to apply for an accountant. Unexpectedly, he missed the application time and was kicked out. He was also abused by the boss of the local Dickinson Metal Factory and even had a gun pointed at his head. When he came to the local tavern in frustration, a one-night stand happened. Unexpectedly, the boyfriend of the woman he had a one-night stand with suddenly broke in, and the bullet penetrated the woman's chest and embedded in William's chest. William instinctively killed the woman's boyfriend, took his horse and fled in a hurry. A thrilling and chased escape journey began...