Aaron (Jonah Hill) is a college graduate who has just left campus and entered the society. His first job is to be an assistant in a record company. But for him, this job is not so happy, because this assistant will be called every day and waved away. What gives Aaron the most headache is that he has to deal with the colleagues and bosses in the company who always tell pornographic jokes and embarrass himself. One day, the boss suddenly assigned Aaron a job: to accompany the company's contracted artist, the famous rock singer Aldous (Russell Brand) to the Greek Theater in Los Angeles to complete his performance. In fact, this is a simple thing, but this Aldous is not an ordinary person. He lives in a drunken state of beating reporters, driving under the influence, taking drugs, and picking up girls in nightclubs every day. In order to get this big man who is in a state of unconsciousness on time at any time of day and night to the Greek Theater, Aaron's journey is destined to be full of many unpredictable accidents...