The foursome of Yingde College, F4, finally graduated. The four decided to plan a trip and chose Spain as their destination. Daomingsi (Jerry Yan) actively invited Shancai (Barbie Hsu) to participate in their Spanish plan. But before leaving, Daomingsi and Shancai quarreled again, and it seemed that the trip to Barcelona was about to fail. But Ximen (Alex Chu), Meizuo (Vanness Wu) and Huaze Lei (Vic Chou), who had many ideas, finally got the couple on a flight to Barcelona. Shancai was very excited to arrive in Barcelona, and Daomingsi was also brewing a plan and decided to propose to Shancai. But on the way to the church, Daomingsi had a car accident and lost his memory. Seeing the happy two people drifting apart, Daomingsi fell in love with another girl after losing his memory; Huaze Lei and Shancai got closer and closer; and Ximen and Meizuo also had new situations. Where will the story of F4 and Shancai go in the end?